Beyond model-based scoring, previous studies have also attempted to rank instructions directly based on length.

Storytelling is a powerful form of communication and may provide insights into factors contributing to gaps in healthcare outcomes. To determine whether Large Language Models (LLMs) can identify potential underlying factors and avenues for intervention, we performed topic-aware hierarchical summarization of narratives from African American (AA) storytellers. Fifty transcribed stories of AA experiences were used to identify topics in their experience using the Latent Dirichlet Allocation (LDA) technique. Stories about a given topic were summarized using an open-source LLM-based hierarchical summarization approach. Topic summaries were generated by summarizing across story summaries for each story that addressed a given topic. Generated topic summaries were rated for fabrication, accuracy, comprehensiveness, and usefulness by the GPT4 model, and the model's reliability was validated against the original story summaries by two domain experts. 26 topics were identified in the fifty AA stories. The GPT4 ratings suggest that topic summaries were free from fabrication, highly accurate, comprehensive, and useful. The reliability of GPT ratings compared to expert assessments showed moderate to high agreement. Our approach identified AA experience-relevant topics such as health behaviors, interactions with medical team members, caregiving and symptom management, among others. Such insights could help researchers identify potential factors and interventions by learning from unstructured narratives in an efficient manner-leveraging the communicative power of storytelling. The use of LDA and LLMs to identify and summarize the experience of AA individuals suggests a variety of possible avenues for health research and possible clinical improvements to support patients and caregivers, thereby ultimately improving health outcomes.

Stress, arising from the dynamic interaction between external stressors, individual appraisals, and physiological or psychological responses, significantly impacts health yet is often underreported and inconsistently documented, typically captured as unstructured free-text in electronic health records. Ambient AI technologies offer promise in reducing documentation burden, but predominantly generate unstructured narratives, limiting downstream clinical utility. This study aimed to develop an ontology for mental stress and evaluate the feasibility of using a Large Language Model (LLM) to extract ontology-guided stress-related information from narrative text. The Mental Stress Ontology (MeSO) was developed by integrating theoretical models like the Transactional Model of Stress with concepts from 11 validated stress assessment tools. MeSO's structure and content were refined using Ontology Pitfall Scanner! and expert validation. Using MeSO, six categories of stress-related information--stressor, stress response, coping strategy, duration, onset, and temporal profile--were extracted from 35 Reddit posts using Claude Sonnet 4. Human reviewers evaluated accuracy and ontology coverage. The final ontology included 181 concepts across eight top-level classes. Of 220 extractable stress-related items, the LLM correctly identified 172 (78.2%), misclassified 27 (12.3%), and missed 21 (9.5%). All correctly extracted items were accurately mapped to MeSO, although 24 relevant concepts were not yet represented in the ontology. This study demonstrates the feasibility of using an ontology-guided LLM for structured extraction of stress-related information, offering potential to enhance the consistency and utility of stress documentation in ambient AI systems. Future work should involve clinical dialogue data and comparison across LLMs.

Things to Do in L.A. Tap to enable a layout that focuses on the article. CDC warns of dramatic rise in dangerous drug-resistant bacteria. The Centers for Disease Control and Prevention warned in a report this week that infections caused by a "super bug" bacteria surged by more than 460% in the United States between 2019 and 2023. This is read by an automated voice. Please report any issues or inconsistencies here .

--The integration of voice-based AI agents in healthcare presents a transformative opportunity to bridge economic and accessibility gaps in digital health delivery. This paper explores the role of large language model (LLM)-powered voice assistants in enhancing preventive care and continuous patient monitoring, particularly in underserved populations. Drawing insights from the development and pilot study of Agent PULSE (Patient Understanding and Liaison Support Engine)--a collaborative initiative between IBM Research, Cleveland Clinic Foundation, and Morehouse School of Medicine--we present an economic model demonstrating how AI agents can provide cost-effective healthcare services where human intervention is economically unfeasible. Our pilot study with 33 inflammatory bowel disease patients revealed that 70% expressed acceptance of AI-driven monitoring, with 37% preferring it over traditional modalities. T echnical challenges, including real-time conversational AI processing, integration with healthcare systems, and privacy compliance, are analyzed alongside policy considerations surrounding regulation, bias mitigation, and patient autonomy. Our findings suggest that AI-driven voice agents not only enhance healthcare scalability and efficiency but also improve patient engagement and accessibility. For healthcare executives, our cost-utility analysis demonstrates huge potential savings for routine monitoring tasks, while technologists can leverage our framework to prioritize improvements yielding the highest patient impact. By addressing current limitations and aligning AI development with ethical and regulatory frameworks, voice-based AI agents can serve as a critical entry point for equitable, sustainable digital healthcare solutions. Healthcare systems worldwide face growing challenges in allocating limited medical resources to meet increasing demand [1], [2]. Traditional healthcare delivery models, centered on episodic patient-provider interactions, often result in significant gaps in continuous care, particularly in preventive health monitoring and chronic disease management [2], [3]. These shortcomings disproportionately affect vulnerable populations, including those with limited access to healthcare facilities [4], lower technological literacy [5], or socio-economic constraints [6]. The advent of Large Language Models (LLMs) and multi-modal AI has opened new avenues for digital health applications [7]-[10], notably in voice-based patient engagement [11], [12]. Unlike earlier rule-based conversational agents, modern AI-driven voice assistants can facilitate context-aware, adaptive, and natural conversations that dynamically adjust to user preferences, health literacy levels, and immediate needs [13]. V oice, as humanity's most intuitive mode of communication, reduces engagement barriers and broadens access to healthcare, especially for underserved communities [12], [14].

While bariatric and metabolic surgery (MBS) is considered the gold standard treatment for severe and morbid obesity, its therapeutic efficacy hinges upon active and longitudinal engagement with multidisciplinary providers, including surgeons, dietitians/nutritionists, psychologists, and endocrinologists. This engagement spans the entire patient journey, from preoperative preparation to long-term postoperative management. However, this process is often hindered by numerous healthcare disparities, such as logistical and access barriers, which impair easy patient access to timely, evidence-based, clinician-endorsed information. To address these gaps, we introduce bRAGgen, a novel adaptive retrieval-augmented generation (RAG)-based model that autonomously integrates real-time medical evidence when response confidence dips below dynamic thresholds. This self-updating architecture ensures that responses remain current and accurate, reducing the risk of misinformation. Additionally, we present bRAGq, a curated dataset of 1,302 bariatric surgery--related questions, validated by an expert bariatric surgeon. bRAGq constitutes the first large-scale, domain-specific benchmark for comprehensive MBS care. In a two-phase evaluation, bRAGgen is benchmarked against state-of-the-art models using both large language model (LLM)--based metrics and expert surgeon review. Across all evaluation dimensions, bRAGgen demonstrates substantially superior performance in generating clinically accurate and relevant responses.

Transitional care may play a vital role for the sustainability of Europe future healthcare system, offering solutions for relocating patient care from hospital to home therefore addressing the growing demand for medical care as the population is ageing. However, to be effective, it is essential to integrate innovative Information and Communications Technology technologies to ensure that patients with comorbidities experience a smooth and coordinated transition from hospitals or care centers to home, thereby reducing the risk of rehospitalization. In this paper, we present an overview of the integration of Internet of Things, artificial intelligence, and digital assistance technologies with traditional care pathways to address the challenges and needs of healthcare systems in Europe. We identify the current gaps in transitional care and define the technology mapping to enhance the care pathways, aiming to improve patient outcomes, safety, and quality of life avoiding hospital readmissions. Finally, we define the trial setup and evaluation methodology needed to provide clinical evidence that supports the positive impact of technology integration on patient care and discuss the potential effects on the healthcare system.

Foundation Models that are capable of processing and generating multi-modal data have transformed AI's role in medicine. However, a key limitation of their reliability is hallucination, where inaccurate or fabricated information can impact clinical decisions and patient safety. We define medical hallucination as any instance in which a model generates misleading medical content. This paper examines the unique characteristics, causes, and implications of medical hallucinations, with a particular focus on how these errors manifest themselves in real-world clinical scenarios. Our contributions include (1) a taxonomy for understanding and addressing medical hallucinations, (2) benchmarking models using medical hallucination dataset and physician-annotated LLM responses to real medical cases, providing direct insight into the clinical impact of hallucinations, and (3) a multi-national clinician survey on their experiences with medical hallucinations. Our results reveal that inference techniques such as Chain-of-Thought (CoT) and Search Augmented Generation can effectively reduce hallucination rates. However, despite these improvements, non-trivial levels of hallucination persist. These findings underscore the ethical and practical imperative for robust detection and mitigation strategies, establishing a foundation for regulatory policies that prioritize patient safety and maintain clinical integrity as AI becomes more integrated into healthcare. The feedback from clinicians highlights the urgent need for not only technical advances but also for clearer ethical and regulatory guidelines to ensure patient safety. A repository organizing the paper resources, summaries, and additional information is available at https://github.com/mitmedialab/medical hallucination.